Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 1 ml
Amount Per Serving
%DV
Vitamin B1 (as thiamine HCl)
4 mg
333%
Riboflavin (as riboflavin 5'-phosphate sodium)
4 mg
308%
Niacin (as niacinamide)
20 mg
125%
Vitamin B6 (as pyridoxine HCl)
10 mg
588%
Folate
333 mcg DFE(200 mcg folic acid)
83%
Vitamin B12 (as cyanocobalamin)
2,000 mcg
83,333%
Biotin
300 mcg
1,000%
Pantothenic Acid (as dexpanthenol)
30 mg
600%

Top Medical Research Studies

8
Vitamin B12 benefits in CFS patients
We investigated the use of vitamin B12 nasal drops in adults with chronic fatigue syndrome (CFS) over three months. A total of 51 patients participated, and we measured their vitamin B12 levels alongside physical activity and fatigue scores.

Remarkably, two-thirds of the participants experienced positive results, including increased activity and better overall scores on fatigue measures. While responders showed significant improvements, the non-responders had only minor increases in vitamin B12 levels.

This indicates that vitamin B12 nasal drops could be a beneficial alternative to injections for many CFS patients.
Read More
We evaluated the impact of B12 injections combined with folic acid on patients with chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME). In our survey of 38 patients, we identified two groups based on their response: Good and Mild responders. Good responders received more frequent and higher doses of B12, leading to significant improvements in their symptoms.

However, Mild responders, many of whom took pain medications, reported minimal progress. Overall, while some patients showed benefits, the effectiveness of B12 treatment varies widely, and further research is needed to understand optimal dosages and drug interactions.
Read More

Most Useful Reviews

9
Significant energy boost
Solgar Sublingual Liquid Vitamin B-12 is an excellent health product that supports energy. The 59 ml package lasts a long time, and the sublingual formula facilitates rapid absorption into the bloodstream. Each dose contains 2,000 micrograms of vitamin B-12, crucial for the nervous system and red blood cell formation. Since starting this vitamin, I have noticed a significant boost in energy, improved mood, and reduced fatigue. The sublingual method is easy to use; just place drops under the tongue and hold before swallowing. I highly recommend Solgar for its effectiveness in enhancing energy and overall health.
Read More
9
Improved mood reported
Perfectly! My mood improves immediately. I previously bought this in a pharmacy and liked the effect. Now, I purchase it here. The numbness in my hands has diminished, and my fatigue has decreased. The role of B12 is critical for the nervous system; without it, other medications may not be effective.
Read More
7.5
Less fatigue noted
The taste is acceptable, albeit not exceptional. I find that this product seems to be working well for me, as I am feeling less fatigued and depressed.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
8
Vitamin B12 benefits in CFS patients
We investigated the use of vitamin B12 nasal drops in adults with chronic fatigue syndrome (CFS) over three months. A total of 51 patients participated, and we measured their vitamin B12 levels alongside physical activity and fatigue scores.

Remarkably, two-thirds of the participants experienced positive results, including increased activity and better overall scores on fatigue measures. While responders showed significant improvements, the non-responders had only minor increases in vitamin B12 levels.

This indicates that vitamin B12 nasal drops could be a beneficial alternative to injections for many CFS patients.
Read More
We evaluated the impact of B12 injections combined with folic acid on patients with chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME). In our survey of 38 patients, we identified two groups based on their response: Good and Mild responders. Good responders received more frequent and higher doses of B12, leading to significant improvements in their symptoms.

However, Mild responders, many of whom took pain medications, reported minimal progress. Overall, while some patients showed benefits, the effectiveness of B12 treatment varies widely, and further research is needed to understand optimal dosages and drug interactions.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Significant energy boost
Solgar Sublingual Liquid Vitamin B-12 is an excellent health product that supports energy. The 59 ml package lasts a long time, and the sublingual formula facilitates rapid absorption into the bloodstream. Each dose contains 2,000 micrograms of vitamin B-12, crucial for the nervous system and red blood cell formation. Since starting this vitamin, I have noticed a significant boost in energy, improved mood, and reduced fatigue. The sublingual method is easy to use; just place drops under the tongue and hold before swallowing. I highly recommend Solgar for its effectiveness in enhancing energy and overall health.
Read More
9
Improved mood reported
Perfectly! My mood improves immediately. I previously bought this in a pharmacy and liked the effect. Now, I purchase it here. The numbness in my hands has diminished, and my fatigue has decreased. The role of B12 is critical for the nervous system; without it, other medications may not be effective.
Read More
7.5
Less fatigue noted
The taste is acceptable, albeit not exceptional. I find that this product seems to be working well for me, as I am feeling less fatigued and depressed.
Read More
7.5
Fatigue reduction observed
I have noticed a reduction in my tiredness and fatigue since using this product.
Read More
7.5
Fatigue alleviated
I’ve been using this product for years, and it significantly helps with fatigue from mental stress. It contains a high level of B12, which I take 1-3 times a week. The product comes with other B vitamins at moderate levels. Taking it sublingually ensures effective absorption, as this method helps B12 enter the bloodstream.
Read More

Frequently Asked Questions

9
Improved mood reported
Perfectly! My mood improves immediately. I previously bought this in a pharmacy and liked the effect. Now, I purchase it here. The numbness in my hands has diminished, and my fatigue has decreased. The role of B12 is critical for the nervous system; without it, other medications may not be effective.
9
Significant energy boost
Solgar Sublingual Liquid Vitamin B-12 is an excellent health product that supports energy. The 59 ml package lasts a long time, and the sublingual formula facilitates rapid absorption into the bloodstream. Each dose contains 2,000 micrograms of vitamin B-12, crucial for the nervous system and red blood cell formation. Since starting this vitamin, I have noticed a significant boost in energy, improved mood, and reduced fatigue. The sublingual method is easy to use; just place drops under the tongue and hold before swallowing. I highly recommend Solgar for its effectiveness in enhancing energy and overall health.
7.5
Fatigue alleviated
I’ve been using this product for years, and it significantly helps with fatigue from mental stress. It contains a high level of B12, which I take 1-3 times a week. The product comes with other B vitamins at moderate levels. Taking it sublingually ensures effective absorption, as this method helps B12 enter the bloodstream.
7.5
Fatigue reduction observed
I have noticed a reduction in my tiredness and fatigue since using this product.
8
Vitamin B12 benefits in CFS patients
We investigated the use of vitamin B12 nasal drops in adults with chronic fatigue syndrome (CFS) over three months. A total of 51 patients participated, and we measured their vitamin B12 levels alongside physical activity and fatigue scores.

Remarkably, two-thirds of the participants experienced positive results, including increased activity and better overall scores on fatigue measures. While responders showed significant improvements, the non-responders had only minor increases in vitamin B12 levels.

This indicates that vitamin B12 nasal drops could be a beneficial alternative to injections for many CFS patients.
We evaluated the impact of B12 injections combined with folic acid on patients with chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME). In our survey of 38 patients, we identified two groups based on their response: Good and Mild responders. Good responders received more frequent and higher doses of B12, leading to significant improvements in their symptoms.

However, Mild responders, many of whom took pain medications, reported minimal progress. Overall, while some patients showed benefits, the effectiveness of B12 treatment varies widely, and further research is needed to understand optimal dosages and drug interactions.

References

  1. van Campen CLM, Riepma K, Visser FC. Open Trial of Vitamin B12 Nasal Drops in Adults With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Comparison of Responders and Non-Responders. Front Pharmacol. 2019;10:1102. doi:10.3389/fphar.2019.01102
  2. Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. doi:10.1371/journal.pone.0124648
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